Fructose and Fat gain Study

AppleAccording to a new study in the Journal of Nutrition, fat-build up from fructose consumption may be greater than consumption of other types of sugars such as glucose and sucrose.

The study involved six young, lean participants who had to drink either: 

A soft drink sweetened with 100% glucos

A soft drink sweetened with 50% glucose and 50% fructose

A soft drink sweetened with 25% glucose and 75% fructose

The tests were random and blinded.

The groups who drank the beverages containing fructose gained more fat at a quicker rate than the glucose group.
We have to remember that the participants in this study were young, healthy and lean.

Therefore it is fair to surmise that people who are less healthy, not as lean and maybe older maybe pre-disposed to even easier fat gain and other health related issues.

Lipogenesis (formation of fat in the body) increased as follows:

  • 100% glucose, lipogenesis = 7.8%
  • 50% glucose and 50% fructose, lipogenesis = 15.9%
  • 25% glucose and 75% fructose, lipogenesis = 16.9%

Also the blood triglyceride levels (i.e. fat in the blood) were between 11% & 29% higher after the consumptions of the 50:50 and 25:75 beverages.
I hope people don’t assume that as a result of this study (and various other related studies) that the consumption of fructose in fruit would also have such an effect.
This study was using pure fructose that is isolated from the high fibre, vitamins and various other co-factors that are found in fruits.  Do not misconceive what the study shows.

However, if you are someone who consumes soft drink full of fructose and various other sugars, then this study is a good indicator of what could happen to you.

Sources available upon request.


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4 Responses to Fructose and Fat gain Study
  1. Jamie Atlas Fitness Blogger
    July 27, 2008 | 10:46 pm

    Great blog entry! What might also be important to note was that ALL groups gained fat from eating glucose or fructose – kind of a would you rather be drowning or bleeding? Of course, you would rather be neither! But we shouldnt for a second think that just because one is less damaging than the other that it makes it okay to put in our body.

    Great point about the fruit vs pure fructose aspect of the study. Our bodies have been eating fructose for years, but usually it comes in the form of an actual piece of fruit. The fructose in this fruit can only be extracted naturally with a large amount of crunching and digestion and fiber and takes much longer for the fructose to actually get to us. So when we take in a fruit juice, the amount of fructose we get is the equivalent of many many pieces of fruit packed into one container (remember when you were a kid and you made some juice – remember how many oranges it took to make just one glass? Remember all the pulp and bits of orange that were left over? That is what your body would normally have to process through). So as you can see, there is a dramatic difference to the body when we take in a real piece of fruit vs a glass of juice. My advice? Take the real fruit! You will also experience reduced hunger and none of the insulin shock that happens with straight juice (insulin shock is when the body releases insulin to counteract the rush of sugar that just hit the body – it has been linked to increased fat stores in studies like the one shown here).

    Jamie Atlas

  2. the health blogger
    July 28, 2008 | 2:10 pm


    Thank you for the great comment and your contribution.

    The insulin shock is very true!

    Feel free to comment anytime.

  3. Shelley
    August 1, 2008 | 6:55 pm

    Thanks for posting the results of this study. More people are becoming aware of the fact that fructose (high fructose corn syrup) is in nearly EVERY processed food, including most low fat or “diet” choices. We all need to get back to whole foods from local markets and away from packages that we pop in to the microwave!

    I’ve bookmarked your blog to come back and get tips from. I would love it if you would pop over to the Be Naturally Well community and add your link so my readers can find you more easily. There are lots of health bloggers out there and people are looking. Here’s the link

    Many Blessings,
    (I am especially interested in the acid/alkaline articles. I would be happy to post them on my blog with you as a ‘guest blogger’ if you would like!)

  4. rv
    August 25, 2008 | 4:42 am

    Yeah, ketchup, ranch, pizza sauce, energy drinks. etc. I know, I cried too when I first heard.

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