Effects of caffeine on productivity and mental fatigue

February 6th, 2008

Coffee Beans

A new study from the Journal of Nutrition shows that caffeine has a positive effect on productivity. The study involved testing the efficacy of two antifatigue substances, caffeine and d-ribose.

Seventeen healthy volunteers were randomised to oral caffeine (200 mg/d), D-ribose (2000 mg/d), or placebo for 8 d.

The candidates were subjected to fatigue-inducing mental tasks: subjects performed a 30-min Uchida-Kraepelin psychodiagnostic test and a 30-min advanced trail-making test on four occasions.

During the tasks, the caffeine supplemented group was better than that of the placebo group. However, post-task fatigue was somewhat different. Though the perceived “…fatigue, motivation, or sleepiness was not significantly different…”, the actual amount of “…plasma branched-chain amino acid levels in the caffeine group were lower than those of the placebo group. Administration of D-ribose had no effect.”

When we get tired due to mental fatigue, plasma branched-chain amino acid (amino acid is protein in its lowest form, e.g. carbohydrate in its lowest form is glucose, fructose etc.) levels decrease.

The results show that the administration of caffeine improved task performance through the enhancement of central nervous system activity without increasing the sensation of fatigue. “However, further decreases in branched-chain amino acid levels indicate that caffeine might promote deeper fatigue than placebo.”

“In contrast, long-term fatigue is sometimes irreversible, and the compensation mechanisms that are useful in reducing acute fatigue are no longer effective. In this view, administration of caffeine might introduce unfavourable situations.”

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Green Tea: Yet another study and yet another benefit!

January 23rd, 2008

green-tea.jpg

A new study published in the Journal of Nutrition suggests that green tea may stop the build-up of fatty deposits in the liver - offering yet another beneficial use - as a lipotropic.

Though the actual study was done with mice, researchers are confident that there could be a similar effect with humans.

Fatty liver is usually a symptomless condition associated with alcoholism, though more recently it has been on the rise due to non-alcohol related factors - nonalcoholic fatty liver disease (NAFLD).

The study suggested that the green tea extract worked by decreasing intestinal fat absorption or altering liver fat metabolism.

“In conclusion, this study provides evidence that GTE (Greent Tea Extract) protects against the development of hepatic steatosis…” (i.e. fatty liver) “…and reduces hepatic injury…” (i.e. liver damage).


Source:
Bruno, R.S., Dugan, C.E., Smyth, J.A., DiNatale, D.A., Koo, S.I., “Green tea extract protects leptin-deficient, spontaneously obese mice from hepatic steatosis and injury”, Journal of Nutrition, Volume 138, Pages 323-331, February 2008.



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